^ Candille, Sophie I.; Kaelin, Christopher B.; Cattanach, Bruce M.; Yu, Bin; Thompson, Darren A.; Nix, Matthew A.; Kerns, Julie A.; Schmutz, Sheila M.; Millhauser, Glenn L.; Barsh, Gregory S. (2007). "A β-Defensin Mutation Causes Black Coat Colour in Domestic Dogs". Science. 318 (5855): 1418–23. doi:10.1126/science.1147880. PMC 2906624. PMID 17947548.
Fast shipping and well packaged. What a great mug - upon initial inspection, it is obvious construction materials are well-designed for its use and it is durable from the table to the dishwasher. The finish is very attractive and the font brings the phrase forward that much better - it will look great in just about any decor. The ergonomics of the handle really adds to the comfort and ease of use allowing for hands and even gloves. It is neither a small nor large mug, neither light nor heavy in weight, but the capacity is perfect for your average cup of coffee. Makes a great gift.
Frito is a tender and sweet pup. He came to rescue as stray and when he first arrived was very submissive. He seemed to be more comfortable outside than in the house, and he didn't touch his toys. In just over a week he is coming out of his shell and although he still exhibits the occasional shyness, he is excited to come when he's called, he is comfortable enough to nap in the middle of the floor or on the couch, and he's a ball of sunshine when we wake up in the morning. Over the past week, his tail has gone from between his legs to wagging with gusto! With time and trust, he will become a typical Lab.
The brainchild of a glass studio in New Jersey, Hot Paws is a unique dog paw print molding kit. After forming the print from their moldable material you send it right back to Hot Paws in a prepackaged container where it will be cast in glass. After a couple of weeks your friend will receive a gorgeous glass impression of their dogs paw which can be used as a paperweight or hung as an ornament.
Ralphie is a morning dog, meaning he is full of energy and ready to go when the sun comes up. At night, he likes to wind down and chill around the house. But if you are up and about, he will run and play at any time. He's smart, a good listener and understands the word No. He's crate and house trained and does not jump on the counter or furniture. Curiosity is strong in Ralphie, which is why he is an occasional fetcher (until he gets interested in something else). The combination of his love for the outdoors and his curiosity means he pulls on the leash, but he has improved his leash skills with some work and would be great with even more. He is social and gets along with every dog we've encountered (even those that don't seem so friendly) and has an easygoing nature that is great with guests (he has not been tested around cats or small children). In the house, he will follow you around all day long to keep you company. He currently does not like to ride in a car, but we are working with him on it. Ralphie is rarely vocal, except if he gets overly excited. Ralphie has moderate energy levels and would prefer a family or a house with a yard. He would also be a loyal companion to a single person or couple with an active lifestyle.
Whatever the case, it's tough to get everybody else gifts and forget about the dogs in your life. Thanks to the number of pet-obsessed companies making everything from baseball jerseys for your bulldog to cans of food that cost more than your entire lunch, there are plenty of options to pick from when making sure your dog gets something on Christmas day or the first night of Hanukkah, even if they have no clue why they're getting it.
Once fetch begins, when it ends isn’t really up to you. With this automated tosser, it can go on as long as your pup wants; she just has to drop the ball in the bucket and watch it launch out the other end. You can even adjust its throwing power to keep the ball-throwing to an inside distance. There’s a model that throws standard tennis balls, and one for small pups that tosses miniature ones.
The lovable Lab needs to be around his family, and is definitely not a backyard dog. If he's left alone for too long, he'll probably tarnish his saintly reputation: A lonely, bored Lab is apt to dig, chew, or find other destructive outlets for his energy. Labs show some variation in their activity levels, but all of them need activity, both physical and mental. Daily 30-minute walks, a romp at the dog park, or a game of fetch, are a few ways to help your Lab burn off energy. However, a puppy should not be taken for too long walks and should play for a few minutes at a time. Labrador Retrievers are considered "workaholics," and will exhaust themselves. It is up to you to end play and training sessions. Labs have such good reputations that some owners think they don't need training. That's a big mistake. Without training, a rambunctious Lab puppy will soon grow to be a very large, rowdy dog. Luckily, Labs take to training well — in fact, they often excel in obedience competitions. Start with puppy kindergarten, which not only teaches your pup good canine manners, but helps him learn how to be comfortable around other dogs and people. Look for a class that uses positive training methods that reward the dog for getting it right, rather than punishing him for getting it wrong. You'll need to take special care if you're raising a Lab puppy. Don't let your Lab puppy run and play on very hard surfaces such as pavement until he's at least two years old and his joints are fully formed. Normal play on grass is fine, as is puppy agility, with its one-inch jumps. Like all retrievers, the Lab is mouthy, and he's happiest when he has something, anything, to carry in his mouth. He's also a chewer, so be sure to keep sturdy toys available all the time — unless you want your couch chewed up. And when you leave the house, it's wise to keep your Lab in a crate or kennel so he's can't get himself into trouble chewing things he shouldn't.
Labrador colouration is controlled by multiple genes. It is possible for recessive genes to re-emerge in later generations. Also, there can sometimes be unexpected pigmentation effects to different parts of the body. Pigmentation effects appear in regard to yellow Labradors, and sometimes chocolate, and hence the majority of this section covers pigmentation within the yellow Labrador. The most common places where pigmentation is visible are the nose, lips, gums, feet, tail, and the rims of the eyes, which may be black, brown, light yellow-brown ("liver", caused by having two genes for chocolate), or several other colours. A Labrador can carry genes for a different colour, for example a black Labrador can carry recessive chocolate and yellow genes, and a yellow Labrador can carry recessive genes for the other two colours. DNA testing can reveal some aspects of these. Less common pigmentations (other than pink) are a fault, not a disqualification, and hence such dogs are still permitted to be shown.
A vigorous dog may or may not be high-energy, but everything he does, he does with vigor: he strains on the leash (until you train him not to), tries to plow through obstacles, and even eats and drinks with great big gulps. These dynamos need lots of training to learn good manners, and may not be the best fit for a home with young kids or someone who's elderly or frail. A low-vigor dog, on the other hand, has a more subdued approach to life.